Disease accounts for 14.4% of yield suppression, costing U.S. soybean growers $5 billion in losses annually (2010 data). Crop protection includes biological, chemical and cultural methods. Host resistance is one of the most economical methods to control soybean yield loss from disease.

According to the 2009 Plant Health Progress publication (Wrather and Koenning), Phytophthora rot, SCN, charcoal rot, SDS and seedling diseases have consistently topped yield-robbing pest and pathogen lists in recent years.